1. 农药类有机污染物的微生物降解与修复;
2. 卤代芳烃化合物的微生物脱卤机制;
3. 代谢型质粒与宿主的适应性进化;
1. 国家重点研发计划,2018YFA0901202,高效降解通路的设计构建与底盘适配,2019/07-2024/06,项目骨干;
2. 国家自然科学基金面上项目,31870095,卤代芳烃代谢质粒pBHB与宿主Comamonas sp. 7D-2的补偿性进化机制,2019/01-2022/12,主持;
3. 中央高校基本科研业务费自主创新重点研究项目,KYZ201742, Pigmentiphaga sp. H8中3,5-二溴-4-羟基苯甲酸的代谢调控机制, 2017/01-2019/12,主持;
4. 国家自然科学基金面上项目,31670111,除草剂利谷隆的微生物代谢机制与矿化关键菌群的结构与功能,2017/01-2020/12,参加;
5. 国家重点研发计划,2016YFD0800203,稻田典型农药多界面迁移规律及生源要素耦合的生物转化机制,2016/01-2020/12,参加;
6. 国家自然科学基金青年基金项目,31400105,菌株Pigmentiphaga sp. H8对3,5-二溴-4-羟基苯甲酸的降解及脱溴机制,2015/01-2017/12,主持;
7. 中央高校基本科研业务费青年项目,KJQN201529,菌株Pigmentiphaga sp.H8对3,5-二溴-4-羟基苯甲酸的降解及脱溴机制,2015/01-2016/12,主持。
Kai Chen, Yang Mu, Shanshan Jian, Xiaoxia Zang, Qing Chen, Weibin Jia, Zhuang Ke, Yanzheng Gao, Jiandong Jiang*. Comparative transcriptome analysis reveals the mechanism underlying 3,5-dibromo-4-hydroxybenzoate catabolism via a new oxidative-decarboxylation pathway. Applied and Environmental Microbiology, 2018, 84(6): e02467-17.
Qing Chen, Xiao-Xia Zang, Xing Hang, Hong-Mei Wang, Wei-Bin Jia, Shun-Peng Li, Jian-Dong Jiang, Kai Chen*. Emticicia soli sp. nov., a new member of the family ‘Flexibacteraceae’, isolated from tetrabromobisphenol A-contaminated soil. International Journal of Systematic and Evolutionary Microbiology, 2017, 67(8):2885-2890.
Qing Chen, Xiao-Xia Zang, Xing Hang, Jing Chen, Hong-Mei Wang, Shun-Peng Li, Jian-Dong Jiang, Kai Chen*. Terrimonas suqianensis sp. nov., isolated from a tetrabromobisphenol A-contaminated soil. Antonie van Leeuwenhoek, 2017: 1-8.
Kai Chen#, Xihui Xu#, Long Zhang#, Zhenjiu Gou, Shunpeng Li, Shiri Freilich*, Jiandong Jiang*. Comparison of four comamonas catabolic plasmids reveals the evolution of pBHB to catabolize haloaromatics. Applied and Environmental Microbiology, 2016, 82(5): 1401-1411.
Kai Chen, Shanshan Jian, Linglong Huang, Zhepu Ruan, Shunpeng Li, Jiandong Jiang. Reductive dehalogenation of 3,5-dibromo-4-hydroxybenzoate by an aerobic strain of Delftia sp. EOB-17. Biotechnology Letters, 2015, 37(12):2395-2401.
Minggen Cheng, Kai Chen, SuhuiGuo, Xing Huang, Jian He, Shunpeng Li, Jiandong Jiang*. PbaR, an IclR-family transcriptional activator for the regulation of the 3-phenoxybenzoate 1’,2’-dioxygenase gene cluster in Sphingobiumwenxiniae JZ-1T. Applied and Environmental Microbiology, 2015, 81(23): 8084-8092.
Kai Chen#, Qing Chen#, Guo-Xiang Wang, Hai-Yan Ni, Jian He, Xin Yan, Jin-Gang Gu*, Shun-Peng Li*. Sphingomonas chloroacetimidivorans sp. nov., a chloroacetamide herbicide-degrading bacterium isolated from activated sludge. Antonie van Leeuwenhoek, 2015, 108:703-710.
Kai Chen, Linglong Huang, Changfeng Xu, Xiaomei Liu, Jian He, Stephen H. Zinder, ShunPeng Li, Jiandong Jiang*. Molecular characterization of the enzymes involved in the degradation of a brominated aromatic herbicide. Molecular Microbiology, 2013, 89: 1121-1139.
Kai Chen, Yuan Liu, Dongmei Mao, Xiaomei Liu, Shunpeng Li, Jiandong Jiang*. An Essential Esterase (BroH) for the Mineralization of Bromoxynil Octanoate by a Natural Consortium of Sphingopyxis sp. Strain OB-3 and Comamonas sp. Strain 7D-2. Journal of Agricultural and Food Chemistry, 2013, 61(47): 11550-11559.
Kai Chen, Xiaomei Liu, Rong Li, Yuan Liu, Hai Hu, Shunpeng Li, Jiandong Jiang*. Isolation of a buprofezin co-metabolizing strain of Pseudomonas sp. DFS35-4 and identification of the buprofezin transformation pathway. Biodegradation, 2011, 22(6): 1135-1142.